Blending Human and Machine Intelligence to Personalise Healthy Longevity

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How we meld what makes us uniquely human with what AI can do is one of the great existential questions of our time—especially in healthcare. Studies show AI can outstrip human decision-makers in complex pattern recognition, and surprisingly, adding humans back into the loop can sometimes reduce accuracy. But raw data alone can feel cold and impersonal.

In my recent conversation with Dr Ash Kapoor of Levitas Clinic (watch ► here), we explored two contrasting strategies for personalization:

1. Data-First, “Press-the-Button” AI

  • Collect everything: blood panels (20+ standard tests), 15–16 aging biomarker groups (telomere length, senescent-cell secretions, etc.), wearables, lifestyle inputs.

  • Train at scale: we’d need on the order of 150,000–200,000 participants (with repeat measures) to power reliable algorithms.

  • Hit “ChatGPT” and out pops your bespoke healthspan roadmap.

The challenge: our datasets are nowhere near that size yet, and it risks feeling like a black-box exercise.

2. Human-First, “Root-Cause” Medicine + AI Co-pilots

Dr Kapoor’s approach flips the script:

  1. 90-minute narrative interview. Track the patient’s life story—early-life traumas, long-buried infections, family history, lifestyle concerns—to pinpoint the most likely drivers of dysfunction.

  2. Targeted testing. Rather than ordering every possible assay, run only the labs that confirm what the history suggests.

  3. AI as your virtual MDT. Imagine a multidisciplinary team—nutritionists, exercise specialists, hormone experts—gathered around the data, each represented by an AI “bot” that chips in with calibrated, up-to-date insights (for example, interpreting microbiome profiles to refine dietary plans).

Real example from our interview: Ash recounts a patient who’d battled anxiety and insomnia for years until a three-week bout of glandular fever in childhood—long ago buried under layers of unspoken trauma—turned out to be the key to resetting their treatment plan and achieving lasting relief.

Which Pathway Will Prevail?

The future is likely hybrid. AI can scale expertise and keep us current; deep human listening uncovers the stories data alone misses.

Your turn:

How do you think we should balance human and AI inputs in healthy longevity? If a human counsellor and an AI system offered different recommendations for your case, which would you trust most—and why?

Reply to this email and let’s shape the next frontier of personalized health together!

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Lisbon’s Longevity Summit: Lessons in Longevity Practicality

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Dr Ash Kapoor on Root-Cause Longevity Medicine, Trauma & AI-Powered Care